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Catalog # MC11018 Cancer Proteins

PB28

PB28. PB28 is a potent, high affinity (Ki = 0.34 nM1) σ2 agonist (1). Its antiproliferative (EC50 ~ 0.4 µM) and cytotoxic (EC50 ~ 12 µM) impacts on glioma and neuroblastoma cell lines suggest it is also a σ1 antagonist (2). PB28 also stopped cell growth in MCF7 breast cancer lines, and was synergistic with doxorubicin
  • 25 mg
  • Cancer Proteins
  • In stock

$210.00

In stock

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Product overview

PB28. PB28 is a potent, high affinity (Ki = 0.34 nM1) σ2 agonist (1). Its antiproliferative (EC50 ~ 0.4 µM) and cytotoxic (EC50 ~ 12 µM) impacts on glioma and neuroblastoma cell lines suggest it is also a σ1 antagonist (2). PB28 also stopped cell growth in MCF7 breast cancer lines, and was synergistic with doxorubicin

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