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Neuromics
Catalog # IPS015 Engineered Cells

Human iPSC – Motor Neurons (TDP-43 M337V, Homozygous)

These human spinal motor neurons (MNs) are derived from a genetically engineered induced Pluripotent Stem Cell (iPSC) line carrying a homozygous M337V mutation in the TARDBP gene, which encodes the TDP-43 protein. This mutation is strongly associated with familial and sporadic Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD).
  • 1,000,000 Cells
  • Engineered Cells
  • In stock

$5,350.00

In stock

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Product overview

These human spinal motor neurons (MNs) are derived from a genetically engineered induced Pluripotent Stem Cell (iPSC) line carrying a homozygous M337V mutation in the TARDBP gene, which encodes the TDP-43 protein. This mutation is strongly associated with familial and sporadic Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD).

Human iPSC - Motor Neurons (TDP-43 M337V, Homozygous) $5,350.00

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